drugset / Trial / NCT07008846
Efficacy of Tofacitinib, Methotrexate Combination Therapy Versus Upadacitinib, Methotrexate Combination Therapy in Moderate to Severe Rheumatoid Arthritis
Phase 3
Active not recruiting
96 enrolled
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
NaSingle-groupOpen-labelHealth-services research
Summary
The aim of this study is to assess the efficacy of upadacitinib, methotrexate combination therapy in comparison to tofacitinib, methotrexate combination therapy in moderate to severe RA patients. This study will guide us to treat RA patients with inadequate response to methotrexate more effectively
Timeline
- Start
- 2025-05-10
- Primary completion
- 2026-09-30
- Completion
- 2026-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methotrexate | Small molecule | — | — |
| Subject | Tofacitinib | Small molecule | — | — |
| Subject | Upadacitinib | Small molecule | — | — |