drugset / Trial / NCT07012395
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficacy and safety of multiple interventions following intravenous (IV) induction and subcutaneous (SC) maintenance treatment.
Timeline
- Start
- 2025-05-27
- Primary completion
- 2027-06
- Completion
- 2028-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | SPY001 | Unknown | — | Intravenous |
| Subject | SPY002 | Unknown | — | Intravenous |
| Subject | SPY003 | Unknown | — | Intravenous |