drugset / Trial / NCT07012512
Adjusted Study Protocol: Within-Subject Paired-Eye Design Comparing Pilocarpine 0.1%, Phentolamine 0.75%, and Combination Therapy for Cyclopentolate Reversal in Children
RandomizedParallel-groupDouble-blindOther
Summary
The study aims at reversing pupillary dilatation. and cycloplegia in children undergoing cycloplegic refraction for eyeglasses prescription and ocular examination. This will be achieved using pilocarpine , phentolamine or a combination. This may help decrease the glare and improve near vision early to decrease unwanted effects of cycloplegic drops.
Timeline
- Start
- 2025-06-01
- Primary completion
- 2025-12-01
- Completion
- 2025-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Phentolamine | Small molecule | 0.75 % | Other |
| Subject | Pilocarpine | Unknown | 0.1 % | Other |