drugset / Trial / NCT07013591
Nicotinamide Mononucleotide in Patients Undergoing CABG Surgery
Phase 2
Recruiting
90 enrolled
Brigham and Women's Hospital
National Institute on Aging (NIA) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The investigators will perform a phase 2a, randomized, double-blind, placebo-controlled clinical trial in adult patients undergoing elective coronary artery bypass grafting (CABG) surgery to investigate the effects of oral nicotinamide mononucleotide (NMN) administration on myocardial NAD+ concentrations and on postoperative markers of myocardial and kidney injury.
Timeline
- Start
- 2026-06-10
- Primary completion
- 2028-10-01
- Completion
- 2029-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MIB-626 | Unknown | 1000 mg | Oral |