drugset / Trial / NCT07016971

CBG/CBD Oil for Chemotherapy-Induced Peripheral Neuropathy

NCT07016971 ↗

Phase 1 Recruiting 12 enrolled Milton S. Hershey Medical Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to learn if a commercially available cannabigerol (CBG)/cannabidiol (CBD) oil is safe, feasible to use, and can help reduce symptoms of chemotherapy-induced peripheral neuropathy (CIPN) in adults who have completed platinum-based chemotherapy for gastrointestinal cancers. The main questions it aims to answer are: Is CBG/CBD oil safe and well-tolerated over a 12-week treatment period? Can participants with CIPN use CBG/CBD oil consistently as part of their care? Does CBG/CBD oil help reduce pain, numbness, or other symptoms of CIPN? Participants will: Take CBG/CBD oil under the tongue (sublingually) twice daily for 12 weeks Complete regular symptom assessments and functional tests during study visits Provide blood samples for cannabinoid and metabolite level testing

Timeline

Start
2026-04-03
Primary completion
2029-04-03
Completion
2029-07-03

Drugs

EvaluationDrugModalityDoseRoute
Subject CBG/CBD Oil Unknown 1 ml Other