drugset / Trial / NCT07022730
Prophylactic Noradrenaline Infusion and Its Impact on Post-induction Hypotension
RandomizedParallel-groupDouble-blindPrevention
Summary
researchers aim to evaluate the influence of prophylactic noradrenaline infusion on post-induction hypotension
Timeline
- Start
- 2025-06-22
- Primary completion
- 2025-09-17
- Completion
- 2025-09-17
Publications
- Results Goertz AW, Lindner KH, Seefelder C, Schirmer U, Beyer M, Georgieff M. Effect of phenylephrine bolus administration on global left ventricular function in patients with coronary artery disease and patients with valvular aortic stenosis. Anesthesiology. 1993 May;78(5):834-41. doi: 10.1097/00000542-199305000-00005.
- Results Czajka S, Putowski Z, Krzych LJ. Post-induction hypotension and intraoperative hypotension as potential separate risk factors for the adverse outcome: a cohort study. J Anesth. 2023 Jun;37(3):442-450. doi: 10.1007/s00540-023-03191-7. Epub 2023 Apr 21.
- Results Tangkulpanich P, Angkoontassaneeyarat C, Trainarongsakul T, Jenpanitpong C. Factors Associated with Postintubation Hypotension Among Patients with Suspected Sepsis in Emergency Department. Open Access Emerg Med. 2023 Nov 14;15:427-436. doi: 10.2147/OAEM.S426822. eCollection 2023.
- Helmy MA, Mostafa MS, Saber AT, Ali MA, Ismail IA, Naguib BA, Elaraby MM, Milad LM. Preemptive noradrenaline infusion: a game-changer against post-induction hypotension in surgical sepsis: a randomized double blind trial. BMC Anesthesiol. 2026 Apr 11;26(1):236. doi: 10.1186/s12871-026-03783-2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Noradrenaline | Unknown | 0.2 ug/kg | — |