drugset / Trial / NCT07025018

Phase I Study of HMPL-306 for the Treatment of Gliomas With IDH1 and/or IDH2 Mutations

NCT07025018

Phase 1 Recruiting 52 enrolled Hutchmed
RandomizedSequentialOpen-labelTreatment

Summary

This study is a multicenter, randomized controlled Phase I clinical study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of HMPL-306 in patients with gliomas harboring IDH1 and/or IDH2 mutations

Timeline

Start
2025-07-15
Primary completion
2026-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject RANOSIDENIB Small molecule

Indications