drugset / Trial / NCT07029568

A Study to See How Safe a New Medicine (NNC0705-0001) is in Healthy People

NCT07029568 ↗

Phase 1 Completed 116 enrolled Novo Nordisk A/S
RandomizedCrossoverQuadruple-blindTreatment

Summary

The study is testing a new study medicine (called NNC0705-0001), as a potential medicine to treat chronic systemic inflammation, which is known for increasing the risk of developing cardiometabolic diseases. The aim of this study is to see if the study medicine is safe, how it works in our body, and what our body does to the study medicine. The participant will either get NNC0705-0001 or placebo (a "dummy medicine" without the active ingredient). Which treatment the participant gets is decided by chance. The study consists of 3 parts: PART A - single ascending dose (SAD); PART B - multiple ascending doses (MAD) and PART C - food effect (FE) on the pharmacokinetic (PK) properties of NNC0705-0001 and will last about 35 days (PART A) and 41 days (PART B and C).

Timeline

Start
2025-06-13
Primary completion
2025-11-04
Completion
2025-12-10

Drugs

EvaluationDrugModalityDoseRoute
Subject NNC0705-0001 Unknown — Oral