drugset / Trial / NCT07030712

A Clinical Study of MK-8294 in Participants With Advanced Solid Tumors (MK-8294-001)

NCT07030712 ↗

Phase 1 Recruiting 67 enrolled Merck Sharp & Dohme LLC
NaSequentialOpen-labelTreatment

Summary

MK-8294, the study medicine, is a type of targeted therapy designed to treat certain solid tumors. The main goals of this study are to learn about the safety of MK-8294 and if people can tolerate it and find the highest dose level of MK-8294 that people can tolerate.

Timeline

Start
2025-07-23
Primary completion
2029-07-01
Completion
2029-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-8294 Unknown 30 ug Intravenous
Subject MK-8294 Unknown 100 ug Intravenous
Subject MK-8294 Unknown 300 ug Intravenous
Subject MK-8294 Unknown 1 mg Intravenous
Subject MK-8294 Unknown 3 mg Intravenous
Subject MK-8294 Unknown 10 mg Intravenous
Subject MK-8294 Unknown 30 mg Intravenous
Subject MK-8294 Unknown 70 mg Intravenous

Indications