drugset / Trial / NCT07032129

Sequential CAR-T Cells Targeting BCMA/GPRC5D in Patients With Relapsed/ Refractory Multiple Myeloma

NCT07032129 ↗

Phase 1/2 Recruiting 60 enrolled Essen Biotech
NaSingle-groupOpen-labelTreatment

Summary

This is an open, single-arm, clinical study to evaluate the efficacy and safety of chimeric antigen receptor T cell immunotherapy (CAR-T) targeting BCMA or GPRC5D or both sequentially in the treatment of Relapsed/ Refractory Multiple myeloma

Timeline

Start
2025-04-29
Primary completion
2027-12-10
Completion
2028-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject BCMA/GPRC5D CAR-T cells Cell therapy — Intravenous

Indications