drugset / Trial / NCT07037511

Effects of Salbutamol in Athletes and Implications for Screening and Sports

NCT07037511

Recruiting 64 enrolled University of British Columbia
RandomizedCrossoverTriple-blindBasic science

Summary

β2-Agonists, commonly used to treat asthma, have also been used by athletes to enhance performance, leading to their ban by the International Olympic Committee in 1972. Research has shown non-asthmatics receive no benefit from these drugs at therapeutic dosages; however, many elite athletes still use them, and asthmatic athletes often win more Olympic medals. In some non-asthmatics, β2-agonists may improve breathing limitations during high intensity exercise, which may improve performance. Therefore, we aim to examine if there is a select group of non-asthmatic individuals who experience breathing limitations that may receive benefit from β2-agonists.

Timeline

Start
2025-10-30
Primary completion
2029-12-31
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Salbutamol Unknown 400 ug Inhaled

Indications