drugset / Trial / NCT07042945

MK-4646 Multiple Dose Trial in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-4646-003)

NCT07042945

Phase 1 Completed 15 enrolled Merck Sharp & Dohme LLC
RandomizedSequentialOpen-labelTreatment

Summary

This study will examine if at least one dose level of MK-4646 can lower HIV-1 viral load in a person's blood by a certain amount. The goals of this study are to learn about the safety of MK-4646 and if people tolerate it; and how HIV-1 viral load may decrease after starting to take MK-4646.

Timeline

Start
2025-07-09
Primary completion
2026-06-05
Completion
2026-06-05

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-4646 Unknown 160 mg Oral
Subject MK-4646 Unknown 460 mg Oral