drugset / Trial / NCT07044297
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
RandomizedParallel-groupDouble-blindTreatment
Summary
Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection. The goals of this study are to learn: * If taking MK-8527 once a month works to prevent HIV-1 infection as well as or better than a standard (usual) pre-exposure prophylaxis (PrEP) taken once a day * About the safety of MK-8527 and if people tolerate it
Timeline
- Start
- 2025-07-31
- Primary completion
- 2027-07-22
- Completion
- 2027-07-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | FTC | Unknown | 200 mg | Oral |
| Subject | MK-8527 | Small molecule | 11 mg | Oral |
| Subject | TDF | Unknown | 245 mg | Oral |