drugset / Trial / NCT07053332

A Study on Immunotherapy Combined With Radiotherapy for Esophagogastric Junction/Gastric Adenocarcinoma

NCT07053332

Phase 2 Not yet recruiting 20 enrolled Jiangsu Cancer Institute & Hospital
NaSingle-groupOpen-labelTreatment

Summary

A single-arm, prospective phase II clinical study of neoadjuvant PD-1/CTLA-4 combination antibody with low-dose radiotherapy in resectable dMMR/MSI-H esophagogastric junction/gastric adenocarcinoma.

Timeline

Start
2025-07
Primary completion
2027-12
Completion
2029-08-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Iparomlimab Monoclonal antibody 5 mg/kg Intravenous
Subject Tuvonralimab Monoclonal antibody 5 mg/kg Intravenous