drugset / Trial / NCT07065682

Effetivity of Dutasteride and Aloe Vera Extract Combination on Angiogenesis and Obstruction on Benign Prostatic Hyperplasia

NCT07065682

Phase 1 Recruiting 84 enrolled Universitas Diponegoro
RandomizedSingle-groupQuadruple-blindTreatment

Summary

This study is a double blinded RCT with pre-post test design on the effect of combination of dutasteride and aloe vera, compared to dutasteride only, on uroflowmetry results, prostate volume, and VEGF serum level among patients with benign prostate hyperplasia. The treatment was given for 12 weeks

Timeline

Start
2023-07-01
Primary completion
2024-12-01
Completion
2027-12-01

Publications

  • Background Nugroho E, Azhar A, Gunadi E. Relationship between Prostate Volume and International Prostate Symptom Score (IPSS) Degree of Tamed Prostate Enlargement on Transabdominal Ultrasonography (TAUS) and Transrectal Ultrasonography (TRUS) Examination. Biomed J Indones. 2021;1(7):112-7

Drugs

EvaluationDrugModalityDoseRoute
Subject Aloe Vera Extract Unknown 380 mg
Comparator Dutasteride Small molecule 0.5 mg