drugset / Trial / NCT07068555
Prostate Cancer Vaccines
NaSingle-groupOpen-labelTreatment
Summary
Tumor antigens are protein fragments produced by cancer cells carrying genetic mutations, and many tumor antigens are similar to normal protein antigens, making them unrecognizable by the immune system. Many tumor vaccines are prepared based on a single tumor antigen. This study is based on multiple target antigens using tumor lysates or synthetic peptides. The immune modulation by dendritic-cell (DC)-based cancer vaccines consists of genetically modified DCs to activate T cells to target cancer cells. The study is based on an advanced cancer vaccine technology, which aims to evaluate the safety and potential benefit of the novel immunomodulatory prostate cancer DC vaccines.
Timeline
- Start
- 2025-06-15
- Primary completion
- 2028-06-15
- Completion
- 2028-12-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Immunomodulatory DC vaccines | Vaccine | 1e+07 cells | Subcutaneous |
| Subject | Immunomodulatory DC vaccines | Vaccine | 2e+07 cells | Subcutaneous |
Indications
No indication recorded.