drugset / Trial / NCT07068555

Prostate Cancer Vaccines

NCT07068555 ↗

Phase 1/2 Recruiting 30 enrolled Shenzhen Geno-Immune Medical Institute
NaSingle-groupOpen-labelTreatment

Summary

Tumor antigens are protein fragments produced by cancer cells carrying genetic mutations, and many tumor antigens are similar to normal protein antigens, making them unrecognizable by the immune system. Many tumor vaccines are prepared based on a single tumor antigen. This study is based on multiple target antigens using tumor lysates or synthetic peptides. The immune modulation by dendritic-cell (DC)-based cancer vaccines consists of genetically modified DCs to activate T cells to target cancer cells. The study is based on an advanced cancer vaccine technology, which aims to evaluate the safety and potential benefit of the novel immunomodulatory prostate cancer DC vaccines.

Timeline

Start
2025-06-15
Primary completion
2028-06-15
Completion
2028-12-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Immunomodulatory DC vaccines Vaccine 1e+07 cells Subcutaneous
Subject Immunomodulatory DC vaccines Vaccine 2e+07 cells Subcutaneous

Indications

No indication recorded.