drugset / Trial / NCT07070024
Efficacy of Microneedling With Vitamin C in Performing Gingival Depigmentation
RandomizedCrossoverSingle-blindTreatment
Summary
The present study will be carried to clinically evaluate the efficacy of microneedling with vitamin C in performing gingival depigmentation in comparison with conventional scalpel and diode laser.
Timeline
- Start
- 2025-07
- Primary completion
- 2026-07-01
- Completion
- 2026-12
Publications
- Results P SM, S S. Comparative Assessment of Gingival Depigmentation Using Scalpel Versus Microneedling With Ascorbic Acid: A Randomized Controlled Trial. Cureus. 2024 Apr 15;16(4):e58285. doi: 10.7759/cureus.58285. eCollection 2024 Apr.
- Results Murthy MB, Kaur J, Das R. Treatment of gingival hyperpigmentation with rotary abrasive, scalpel, and laser techniques: A case series. J Indian Soc Periodontol. 2012 Oct;16(4):614-9. doi: 10.4103/0972-124X.106933.
- Results Mostafa D Sr, A Alaizari N, M AlOtaibi S, Ahmed Aldosari N, Rabie Al-Anazi J, S Alsughayer R, M AlFayir H, S AlHarthi M, H AlAnazi M. Gingival Depigmentation Using Microneedling Technique With Topical Vitamin C: A Prospective Case Series. Cureus. 2023 Feb 23;15(2):e35345. doi: 10.7759/cureus.35345. eCollection 2023 Feb.
- Results Abramson JH. The cornell medical index as an epidemiological tool. Am J Public Health Nations Health. 1966 Feb;56(2):287-98. doi: 10.2105/ajph.56.2.287. No abstract available.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Vitamin C | Other / unclassified | 1000 mg/ml | Topical |