Topical Icariin on Acne and Acne Scars

Summary

The goal of this clinical trial is to examine whether topical application of icariin can improve acne and atrophic acne scars in adults. The main questions it aims to answer are: * Does icariin reduce the number of facial acne lesions and acne scars? * What histological changes occur in acne or scar tissue after using icariin? Researchers will compare icariin to a vehicle control (3% ethanol solution) to assess its relative efficacy. Participants will: * Apply icariin or control solution to each side of the face twice daily for 2 months * Visit the clinic every 4 weeks for checkup * Receive skin biopsies before and after the study period, if they consent to this procedure

Timeline

Start

2023-03-21

Primary completion

2025-12-31

Completion

2025-12-31

Drugs

Indications