drugset / Trial / NCT07076914
Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation Therapy
Phase 2
Not yet recruiting
58 enrolled
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
RandomizedParallel-groupOpen-labelTreatment
Summary
A randomized controlled trial to assess the impact of prophylactic proton pump inhibitor use to improve esophagitis in lung cancer patients undergoing radiation. Patients will be randomized into a standard of care arm or the prophylactic proton pump (daily) arm.
Timeline
- Start
- 2025-10-02
- Primary completion
- 2028-01-02
- Completion
- 2032-10-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lansoprazole | Other / unclassified | — | — |
| Subject | Pantoprazole | Other / unclassified | — | — |
| Subject | Rabeprazole | Small molecule | — | — |