drugset / Trial / NCT07081633

Durvalumab and Tremelimumab With Lenvatinib as First-line Treatment in Patients With Unresectable Hepatocellular Carcinoma

NCT07081633

Phase 2 Active not recruiting 114 enrolled AstraZeneca
NaSingle-groupOpen-labelTreatment

Summary

This is a Phase II, single-arm, multicentre study, assessing the efficacy and safety of durvalumab and tremelimumab with lenvatinib in participants with unresectable HCC.

Timeline

Start
2025-08-05
Primary completion
2026-11-30
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody Intravenous
Subject Lenvatinib Small molecule Oral
Subject Tremelimumab Monoclonal antibody Intravenous