drugset / Trial / NCT07082868

A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)

NCT07082868

Phase 1 Recruiting 26 enrolled Memorial Sloan Kettering Cancer Center
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to find out whether the combination of epcoritamab and ibrutinib is a safe treatment approach that causes few or mild side effects in people with relapsed/refractory primary central nervous system lymphoma (PCNSL) or secondary central nervous system lymphoma (SCNSL).

Timeline

Start
2025-08-13
Primary completion
2028-08
Completion
2028-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Epcoritamab Monoclonal antibody Subcutaneous
Subject Ibrutinib Small molecule