drugset / Trial / NCT07082920
A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
Non-randomizedSequentialOpen-labelTreatment
Summary
The purpose of this study is to identify the recommended phase 2 combination dose (RP2CD) of JNJ-78278343 in combination with JNJ-95298177 in Part 1 (Dose confirmation) of the study and to determine how safe and tolerable the RP2CD is for treatment of participants with metastatic castration-resistant prostate cancer (mCRPC; a stage of prostate cancer where the cancer has spread beyond the prostate and is resistant to hormonal therapy) in Part 2 (Dose expansion) of study.
Timeline
- Start
- 2025-07-07
- Primary completion
- 2027-01-28
- Completion
- 2027-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ARX517 | Monoclonal antibody | — | Intravenous |
| Subject | Pasritamig | Other / unclassified | — | Intravenous |