Evaluation of Tretinoin Cream on the Integrity of Aged Forearm Skin

Summary

The purpose of this research is to determine whether once nightly application of tretinoin 0.1% cream to forearm skin reduces the frequency of skin tears and bruising (solar purpura), and changes skin thickness over a period of 6 months.

Timeline

Start

2025-07-14

Primary completion

2026-05-23

Completion

2026-05-24

Publications

• Background Sitohang IBS, Makes WI, Sandora N, Suryanegara J. Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials. Int J Womens Dermatol. 2022 Mar 25;8(1):e003. doi: 10.1097/JW9.0000000000000003. eCollection 2022 Mar.

Drugs

Indications