Comparing Post-intravitreal Injection Pain Scores Using Loteprednol, Bromfenac Sodium, and Artificial Tears Over a 24-hour Period

Phase 4 Completed 77 enrolled Retina Research Institute, LLC Bausch & Lomb Incorporated · collab

RandomizedParallel-groupOpen-labelPrevention

Summary

The goal of this clinical trial is to learn how various topical drops (bromfenac, loteprednol, and artificial tears) fare in alleviating post-intravitreal injection pain. The main questions it aims to answer are: \- Do bromfenac sodium and/or loteprednol etabonate improve post-injection pain scores compared to preservative-free artificial tears? Participants will: * Receive one drop of the topical drops five minutes prior to their regularly scheduled intravitreal injection. Depending on the treatment arm, they will also administer drops on their own at home up to 3 times per day on the day of their procedure. * They will answer a standardized pain score survey at 4 hours and 24 hours following their intravitreal injection and convey their results to study coordinators by phone.

Timeline

Start: 2021-08-20
Primary completion: 2022-12-07
Completion: 2022-12-08

Publications

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Bromfenac	Other / unclassified	0.07 %	Topical
Comparator	Loteprednol Etabonate	Other / unclassified	0.38 %	Topical

Comparing Post-intravitreal Injection Pain Scores Using Loteprednol, Bromfenac Sodium, and Artificial Tears Over a 24-hour Period

Summary

Timeline

Publications

Drugs

Indications