drugset / Trial / NCT07091136
Exploration of Manidipine to Reverse Aortic Valve Calcification
Phase 2
Not yet recruiting
100 enrolled
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RandomizedParallel-groupTriple-blindTreatment
Summary
This is a prospective, randomized, comparative, clinical trial conducted by Wuhan Union Hospital that aims to evaluate the efficacy and safety of manidipine compared to placebo in patients with calcific aortic valve disease with mild aortic valve stenosis.
Timeline
- Start
- 2025-08-01
- Primary completion
- 2026-08-01
- Completion
- 2026-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MANIDIPINE 6300 | Small molecule | 10 mg | — |
| Subject | MANIDIPINE 6300 | Small molecule | 20 mg | — |