drugset / Trial / NCT07092709
Tenecteplase for Intravenous Stroke Thrombolysis in Recent DOAC Users
RandomizedParallel-groupQuadruple-blindTreatment
Summary
An investigator-initiated, multicenter, randomized, placebo-controlled, double-blind trial to determine the efficacy and safety of intravenous tenecteplase thrombolysis in acute ischemic stroke (AIS) patients with recent direct oral anticoagulants (DOACs) intake in improving the 90-day functional outcome.
Timeline
- Start
- 2025-08-14
- Primary completion
- 2028-09-01
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tenecteplase | Protein / enzyme biologic | 0.25 mg/kg | Intravenous |