drugset / Trial / NCT07093398

A Phase 1 Study to Assess Food Effect on the Pharmacokinetics of D3S-001 in Healthy Adult Participants

NCT07093398

Phase 1 Completed 26 enrolled D3 Bio (Wuxi) Co., Ltd Fortrea · collab
RandomizedCrossoverOpen-labelTreatment

Summary

The goal of this clinical trial is to Assess the Effect of Food on the Pharmacokinetics (PK) of D3S-001 in Healthy Adult Participants. The main question\[s\] it aims to answer are: 1. Evaluate the PK of D3S-001 administered in the fasted and fed state in healthy adult participants. 2. Evaluate the safety and tolerability of D3S-001 administered in the fasted and fed state in healthy adult participants. Potential participants will be screened within 28 days prior to the first dose. Participants will be admitted into the clinical research unit (CRU) on Day -1 and will be confined until end of study (EOS) or until early termination. On Day 1, participants will be randomised to Group 1 or Group 2. Participants will receive Treatment A or Treatment B in each of 2 periods (Periods 1 and 2; Study Days 1 and 4), once under fasted conditions (Treatment A) and once under fed conditions (Treatment B). Each participant will receive both treatments.

Timeline

Start
2025-07-11
Primary completion
2025-11-12
Completion
2025-11-17

Drugs

EvaluationDrugModalityDoseRoute
Subject D3S-001 Small molecule 600 mg Oral

Indications

No indication recorded.