drugset / Trial / NCT07095205
PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine.
Phase 4
Recruiting
14 enrolled
Stony Brook University
National Institute of Mental Health (NIMH) · collabNational Institutes of Health (NIH) · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
In the brain, certain nerve cells communicate using a chemical called acetylcholine. Acetylcholine is thought to be important for several functions including mood, memory and wakefulness. The purpose of this study is to explore the role of these nerve cells in depression. Also, we would like to understand how nicotine, the study drug, works in depression and how it affects these nerve cells. To do this, brain imaging will be used before and after this treatment.
Timeline
- Start
- 2024-10-03
- Primary completion
- 2029-09-30
- Completion
- 2029-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nicotine | Unknown | 21 mg | Other |