drugset / Trial / NCT07097038
Analgesic Effect and Safety of Oliceridine and Oxycodone in Vitrectomy
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Traditional opioid analgesia is a method to treat moderate to severe pain. However, the use of opioids is not without risks. When treating acute pain, patients may have hypotension, respiratory depression, hypoxia, nausea and vomiting, irritability and pruritus. The aim of this study was to evaluate the analgesic effect and safety of g-protein-biased μ - opioid receptor agonists Oliceridine and oxycodone in vitrectomy.
Timeline
- Start
- 2025-07
- Primary completion
- 2025-12
- Completion
- 2026-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oliceridine | Other / unclassified | 0.015 mg/kg | — |
| Comparator | Oxycodone | Other / unclassified | 0.04 mg/kg | — |
Indications
No indication recorded.