drugset / Trial / NCT07097064

Evaluation of the Stereotactic MR-guided Adaptive Radiotherapy for Locally Advanced Pancreatic Cancers

NCT07097064 ↗

Phase 2 Not yet recruiting 160 enrolled Institut du Cancer de Montpellier - Val d'Aurelle
RandomizedParallel-groupOpen-labelTreatment

Summary

Pancreatic cancer is on the rise, and is set to become the 2nd leading cause of cancer deaths by 2030. Its prognosis is very poor, with a 5-year survival rate of just 5.5%. Curative surgery with chemotherapy improves survival, but only 20% of patients are eligible. For locally advanced forms, radiotherapy, notably in the form of MRI-guided adaptive stereotactic radiotherapy (SMART), is showing promising results in terms of survival and local control, but still requires prospective validation.

Timeline

Start
2025-09
Primary completion
2028-09
Completion
2033-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 800 mg/m2 —
Subject Capecitabine Small molecule 825 mg/m2 —