drugset / Trial / NCT07102706

Phase I Trial of GR1803 Injection in Patients With RRMM

NCT07102706

Phase 1/2 Completed 76 enrolled Genrix (Shanghai) Biopharmaceutical Co., Ltd.
Non-randomizedSequentialOpen-labelTreatment

Summary

All subjects will receive GR1803 injection until intolerable toxicity or investigator-assessed disease progression occurs (except in cases of disease progression due to discontinuation of the drug as a result of an adverse event) or until the subject has been administered the drug for 52 weeks or until the subject withdraws consent or until the investigator determines that the subject needs to be discontinued.

Timeline

Start
2022-05-27
Primary completion
2025-05-20
Completion
2025-05-20

Drugs

EvaluationDrugModalityDoseRoute
Subject GR1803 Unknown 0.02 ug/kg
Subject GR1803 Unknown 1 ug/kg
Subject GR1803 Unknown 10 ug/kg
Subject GR1803 Unknown 30 ug/kg
Subject GR1803 Unknown 90 ug/kg
Subject GR1803 Unknown 180 ug/kg
Subject GR1803 Unknown 240 ug/kg
Subject GR1803 Unknown 300 ug/kg
Subject GR1803 Unknown 360 ug/kg

Indications