drugset

drugset / Trial / NCT07105371

Patients With ALS and Other Motor Disorders Will be Treated With Mesenchymal Cell Exosome Solution

NCT07105371 ↗

Phase 1 Completed 18 enrolled The Foundation for Orthopaedics and Regenerative Medicine

NaSingle-groupOpen-labelTreatment

Summary

Patients with ALS and other Motor Discorders will be treated with mesenchymal cell exosome solution.

Timeline

Start: 2024-07-14
Primary completion: 2025-03-14
Completion: 2025-03-14

Publications

Prodromos CC, Del Villar R, Jin MY, Abd-Elsayed A, Candido K. Exosome-rich mesenchymal stem cell secretome improves strength in patients with amyotrophic lateral sclerosis, Kennedy disease, congenital myasthenic syndrome and Lewy body dementia. Am J Stem Cells. 2025 Oct 15;14(4):217-229. doi: 10.62347/FTXA8845. eCollection 2025.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	AlloEx exosomes	Other / unclassified	—	Intranasal

Indications