drugset / Trial / NCT07106684

ASCT Combined With BCMA CAR-T and GPRC5D/CD3 BiTEs Maintenance for Transplant-Eligible Primary Plasma Cell Leukemia

NCT07106684

NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, single-arm, phase II study to evaluate the efficacy and safety of autologous stem cell transplantation combined with BCMA CAR-T therapy followed by GPRC5D/CD3 bispecific antibody maintenance in transplant-eligible patients with primary plasma cell leukemia.

Timeline

Start
2025-08-10
Primary completion
2027-08-01
Completion
2029-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject BCMA CAR-T Cell therapy 3e+06 cells/kg Other

Indications