drugset / Trial / NCT07107490

A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER

NCT07107490

Phase 1 Recruiting 122 enrolled Chugai Pharmaceutical
Non-randomizedSequentialOpen-labelTreatment

Summary

This study is a phase I, open-label, multicenter trial designed to evaluate the safety, tolerability, pharmacokinetics, immunogenicity, and antitumor activity of ALPS12 in patients with extensive-stage small cell lung cancer. The study consists of two parts: a dose-escalation part and an expansion part.

Timeline

Start
2025-10-08
Primary completion
2028-09-30
Completion
2028-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject ALPS12 Unknown Intravenous
Background Obinutuzumab Monoclonal antibody Intravenous