drugset / Trial / NCT07109284

SKB264 Combined With KL-A167 Neoadjuvant Therapy for Early-stage, High-risk ER+/HER2- Breast Cancer

NCT07109284

Phase 2 Not yet recruiting 55 enrolled West China Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study aimed to evaluate the efficacy and safety of SKB264 combined with KL-A167 as neoadjuvant therapy in early-stage high-risk ER+HER2- breast cancer patients.

Timeline

Start
2025-09
Primary completion
2028-01
Completion
2030-12

Drugs

EvaluationDrugModalityDoseRoute
Subject KL-A167 Unknown 900 mg Intravenous
Subject Sacituzumab Tirumotecan Other / unclassified 5 mg/kg Intravenous