drugset / Trial / NCT07126665

A Study of MHB088C Combined With MHB039A in Patients With Advanced Malignant Solid Tumors

NCT07126665

Phase 1/2 Recruiting 116 enrolled Minghui Pharmaceutical (Hangzhou) Ltd
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a first-in-human, open-label, multicenter Phase I/II study of MHB088C combined with MHB039A in patients with advanced malignant solid tumors. The study was designed to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of MHB088C and MHB039A combination therapy.

Timeline

Start
2025-09-18
Primary completion
2029-08
Completion
2031-08

Drugs

EvaluationDrugModalityDoseRoute
Subject MHB039A Unknown Intravenous
Subject MHB088C Monoclonal antibody Intravenous

Indications