drugset / Trial / NCT07128355
Botensilimab, Balstilimab, and SBRT in Colorectal Cancer
NaSingle-groupOpen-labelTreatment
Summary
This is a single-arm pilot feasibility study evaluating the combination of Botensilimab and Balstilimab with Radiation Therapy (RT) in Non-Microsatellite Instability High (MSI-H) or Proficient Mismatch Repair (pMMR) chemorefractory colorectal cancer (CRC) with liver metastasis.
Timeline
- Start
- 2026-05-12
- Primary completion
- 2027-01-01
- Completion
- 2027-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Balstilimab | Monoclonal antibody | — | Intravenous |
| Subject | Botensilimab | Monoclonal antibody | — | Intravenous |