drugset / Trial / NCT07131280
National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Single vs Repeated Cycle of Granulocyte Colony-Stimulating Factor (GCSF) & Darbepoetin in Early Decompensated Cirrhosis
Not yet recruiting
110 enrolled
Institute of Liver and Biliary Sciences, India
Indian Council of Medical Research · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Chronic liver disease is a growing health concern, with limited access to liver transplants. This study addresses the urgent need for alternatives by exploring regenerative therapies, like G-CSF, to boost the liver's natural repair. The goal is to develop safe, effective, and accessible treatments for patients who cannot undergo transplant.
Timeline
- Start
- 2025-09
- Primary completion
- 2031-07
- Completion
- 2031-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Darbepoetin alfa | Protein / enzyme biologic | 40 ug | Subcutaneous |
| Subject | G-CSF | Protein / enzyme biologic | 5 ug/kg | Subcutaneous |