drugset / Trial / NCT07134231
Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model
RandomizedCrossoverQuadruple-blindOther
Summary
Clinical study to evaluate the anti-cavity effectiveness of three dentrifices using an intra-oral enamel Demineralization and Remineralization In-Situ Model. This is a six-week duration, Phase III, single-center, triple-blind crossover study. Thirty-six healthy adults will be randomly allocated to three groups for the treatment phases, which are interspersed with washout periods.
Timeline
- Start
- 2025-10-09
- Primary completion
- 2025-12-11
- Completion
- 2025-12-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluoride | Other / unclassified | — | Topical |
| Subject | Fluoride free toothpaste in a PCC/RNCC base | Unknown | — | Topical |
| Subject | Fluoride free toothpaste in a chalk base | Unknown | — | Topical |