drugset / Trial / NCT07136012

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

NCT07136012 ↗

Phase 3 Recruiting 11000 enrolled Amgen
RandomizedParallel-groupDouble-blindTreatment

Summary

The primary objective is to evaluate the effect of olpasiran, compared to placebo, on the risk for coronary heart disease death (CHD death), myocardial infarction, or urgent coronary revascularization in participants at risk for a first major cardiovascular event with elevated lipoprotein(a) (Lp\[a\]).

Timeline

Start
2025-08-22
Primary completion
2031-10-20
Completion
2031-10-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Olpasiran Unknown — Subcutaneous