drugset / Trial / NCT07137598

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

NCT07137598

Phase 2 Recruiting 160 enrolled Hoffmann-La Roche
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will assess the efficacy and safety of Afimkibart (also known as RO7790121) compared with placebo in participants with moderate to severe rheumatoid arthritis (RA) who have an inadequate response or intolerance to TNF and/or JAK inhibitors.

Timeline

Start
2025-12-05
Primary completion
2027-04-19
Completion
2027-10-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Afimkibart Monoclonal antibody Subcutaneous

Indications