drugset / Trial / NCT07138508
Oral Nicorandil for Prevention of No Reflow Phenomenon in Anterior STEMI Patients Undergoing PPCI
Phase 1/2
Completed
300 enrolled
Ain Shams University
Misr University for Science and Technology · collab
RandomizedParallel-groupSingle-blindPrevention
Summary
Aim of the study is to Investigate the potential role of oral nicorandil in preventing the No reflow phenomenon in anterior ST-segment elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention (PPCI). Assess whether nicorandil, a potassium channel activator, can effectively enhance myocardial perfusion in this specific clinical context. * In a randomized controlled trial study * All recruited patients were randomized to either the treatment or control group in a ratio of 1:1 using a computer-generated randomization sequence in relation to the order of participation in the study. Patients fulfilling the inclusion criteria and consenting to participate in the study were recruited.
Timeline
- Start
- 2024-03-10
- Primary completion
- 2025-02-28
- Completion
- 2025-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Nicorandil | Other / unclassified | 20 mg | Oral |