drugset / Trial / NCT07140315

DK222 Study at Hopkins

NCT07140315 ↗

NaSingle-groupOpen-labelTreatment

Summary

This Phase 1 clinical trial will test a new drug called \[18F\]DK222 in people with cancer. The goal is to see if the drug is safe, how it spreads through the body, how long it stays in the body, and how much radiation it gives off. \[18F\]DK222 is designed to attach strongly and specifically to a protein called PD-L1, which helps cancer hide from the immune system. This is a first in human study to collect preliminary safety and toxicity data of \[18F\]DK222.

Timeline

Start
2026-07-01
Primary completion
2027-07-01
Completion
2027-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject [18F]DK222 Diagnostic / imaging agent — Intravenous