drugset / Trial / NCT07141381
A Study to Evaluate the Effect of Food and a Proton Pump Inhibitor on the Pharmacokinetics of VRN110755
RandomizedCrossoverOpen-labelTreatment
Summary
This is a Phase 1, open-label, randomized, single-center study to evaluate the effect of food and a proton pump inhibitor (PPI) on the pharmacokinetics (PK) of VRN110755 in healthy adult participants. The primary aim of this study is to assess the impact of food and rabeprazole co-administration on the systemic exposure of VRN110755. Safety and tolerability will also be evaluated.
Timeline
- Start
- 2025-08-27
- Primary completion
- 2025-12-17
- Completion
- 2026-04-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rabeprazole | Small molecule | 20 mg | Oral |
| Subject | VRN110755 | Unknown | 80 mg | Oral |
Indications
No indication recorded.