drugset / Trial / NCT07150767

A Clinical Study to Explore the Safety, Tolerability, and Efficacy of Recombinant Human nsIL12 Oncolytic Adenovirus Injection (BioTTT001) Combined With Neoadjuvant Treatment for Locally Advanced Breast Cancer

NCT07150767

NaSingle-groupOpen-labelTreatment

Summary

A clinical study to explore the safety, tolerability, and efficacy of recombinant human nsIL12 oncolytic adenovirus injection (BioTTT001) combined with neoadjuvant treatment for locally advanced breast cancer.This study is a single-arm, open-label, single-center dose-escalation and expansion trial.

Timeline

Start
2025-03-26
Primary completion
2027-03-26
Completion
2027-03-26

Drugs

EvaluationDrugModalityDoseRoute
Subject BioTTT001 Unknown 5e+10 vg Other
Subject BioTTT001 Unknown 2e+11 vg Other
Subject BioTTT001 Unknown 5e+11 vg Other

Indications