drugset / Trial / NCT07150767
A Clinical Study to Explore the Safety, Tolerability, and Efficacy of Recombinant Human nsIL12 Oncolytic Adenovirus Injection (BioTTT001) Combined With Neoadjuvant Treatment for Locally Advanced Breast Cancer
NaSingle-groupOpen-labelTreatment
Summary
A clinical study to explore the safety, tolerability, and efficacy of recombinant human nsIL12 oncolytic adenovirus injection (BioTTT001) combined with neoadjuvant treatment for locally advanced breast cancer.This study is a single-arm, open-label, single-center dose-escalation and expansion trial.
Timeline
- Start
- 2025-03-26
- Primary completion
- 2027-03-26
- Completion
- 2027-03-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BioTTT001 | Unknown | 5e+10 vg | Other |
| Subject | BioTTT001 | Unknown | 2e+11 vg | Other |
| Subject | BioTTT001 | Unknown | 5e+11 vg | Other |