drugset / Trial / NCT07152210
Clinical Study on the Safety and Preliminary Efficacy of CDH17/GUCY2C CAR-T in the Treatment of Patients With Advanced Colorectal Cancer
Withdrawn
Guangzhou Bio-gene Technology Co., Ltd
NaSingle-groupOpen-labelTreatment
Summary
This study is a single-arm, single-center investigator-initiated trial (IIT) designed to evaluate the safety and preliminary efficacy of CDH17/GUCY2C CAR-T cell therapy in patients with advanced colorectal cancer, as well as to assess its pharmacodynamic (PD) and pharmacokinetic (PK) profiles.
Timeline
- Start
- 2024-12-11
- Primary completion
- 2026-03-02
- Completion
- 2026-03-02
Outcome
Outcome not reported
Stopped (Business): “Due to corporate strategic adjustment.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CDH17/GUCY2C CAR-T | Cell therapy | 1e+06 cells/kg | Intravenous |
| Subject | CDH17/GUCY2C CAR-T | Cell therapy | 5e+06 cells/kg | Intravenous |