drugset / Trial / NCT07153471

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

NCT07153471

Phase 3 Recruiting 800 enrolled Eli Lilly and Company
RandomizedParallel-groupSingle-blindTreatment

Summary

The GZPT master protocol will support two independent studies, J2A-MC-GZT1 and J2A-MC-GZT2. Each study will see how well and safely orforglipron works in people with obesity or overweight who have osteoarthritis (OA) of the knee with pain. Participation in the study will last about 74 weeks.

Timeline

Start
2025-09-15
Primary completion
2028-04
Completion
2028-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Orforglipron Small molecule Oral

Indications