drugset / Trial / NCT07156136

Study of IMC-P115C in Advanced PRAME-Positive Cancers

NCT07156136 ↗

Phase 1 Recruiting 140 enrolled Immunocore Ltd
NaSequentialOpen-labelTreatment

Summary

Phase 1 First-in-human study of the safety and efficacy of IMC-P115C as a single agent and in combination with standard of care (SOC) agents in participants with advanced PRAME positive cancers. IMC-P115C is a half-life extended (HLE) ImmTAC targeting PRAME.

Timeline

Start
2024-11-07
Primary completion
2027-09-30
Completion
2029-08-30

Drugs

EvaluationDrugModalityDoseRoute
Subject IMC-P115C Protein / enzyme biologic — Intravenous

Indications