drugset / Trial / NCT07160257

A Study to Evaluate the Effect of Maridebart Cafraglutide on Insulin Sensitivity and β-cell Function in Participants With Type 2 Diabetes Mellitus

NCT07160257

Phase 1 Active not recruiting 56 enrolled Amgen
RandomizedParallel-groupDouble-blindTreatment

Summary

The primary objective of this study is to determine the effect of maridebart cafraglutide relative to placebo on insulin sensitivity in participants with Type 2 Diabetes Mellitus (T2DM) treated with stable dose of metformin.

Timeline

Start
2025-08-05
Primary completion
2026-11-15
Completion
2027-03-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Maridebart Cafraglutide Unknown Subcutaneous