drugset / Trial / NCT07162363

Synergistic Minimally Invasive Surgery and Deferoxamine in ICH

NCT07162363

Phase 2/3 Not yet recruiting 240 enrolled University of Illinois at Chicago
RandomizedParallel-groupSingle-blindTreatment

Summary

This is a multicenter, randomized, open-label trial designed to evaluate the safety, feasibility, and efficacy of combining minimally invasive surgery (MIS) with intravenous deferoxamine (DFX) for the treatment of spontaneous intracerebral hemorrhage (ICH), compared to standard medical care. This trial represents the first investigation of a dual-modality approach in ICH, integrating mechanical clot evacuation with biochemical neuroprotection, with the goal of improving neurological outcomes.

Timeline

Start
2026-03-01
Primary completion
2028-12-30
Completion
2028-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Deferoxamine Other / unclassified 32 mg/kg Intravenous